Circulating MOTS-c after weight loss: a small longitudinal study
Researchers compared lean and obese adults, with a small subset measured again after bariatric surgery.
Human physiology studyPaper year: 2026MOTS-c
01 / DESIGN
What was studied?
Researchers compared lean and obese adults, with a small subset measured again after bariatric surgery.
02 / FINDINGS
What did the researchers report?
Circulating levels were higher in the obesity group and showed nonlinear metabolic associations. They did not clearly change after postoperative weight reduction in the follow-up subset.
03 / INTERPRETATION
What are the limits?
Only a small number had repeat measurements. Endogenous biomarker patterns do not demonstrate the effects of exogenous MOTS-c or establish a diagnostic threshold.
Original editorial summary by Sulan Peptide. Based on the source abstract; consult the full paper for methods, analyses, funding and disclosures.
RESEARCH CONTEXT
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